ABSTRACT An integrative review was undertaken to analyze studies published since 1998 on the use of high-fidelity patient simulation (HFPS) in undergraduate nursing education. This review found that HFPS benefits nursing students in terms of knowledge, value, realism, and learner satisfaction; findings were mixed in the areas of student confidence, knowledge transfer, and stress. Further research in these and other areas will determine whether its increased use is warranted. **********